The Dietary Protein Source Modulates Obesity Development and Induces Distinct Plasma Lipid Profiles and Transcriptome Profiles in Liver and Adipose Tissue
Lene S. Myrmel, Even Fjære, Annette Bernhard, Josef D. Rasinger, Ole Jakob Nøstbakken, Helene Søiland, Philipp Rausch, Martin von Bergen, Ulrike Rolle‐Kampzcyk, Liang Xiao, Hanlin Zhou, Guibo Li, Karsten Kristiansen, Lise Madsen · 2026
Read The Dietary Protein Source Modulates Obesity Development and Induces Distinct Plasma Lipid Profiles and Transcriptome Profiles in Liver and Adipose Tissue by Lene S. Myrmel, Even Fjære, Annette Bernhard, Josef D. Rasinger, Ole Jakob Nøstbakken, Helene Søiland, Philipp Rausch, Martin von Bergen, Ulrike Rolle‐Kampzcyk, Liang Xiao, Hanlin Zhou, Guibo Li, Karsten Kristiansen, Lise Madsen (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13454709.txt.
Description
Myrmel and colleagues ask whether the source of dietary protein changes how easily mice become obese in this 2026 study. Dairy and seafood proteins seem less fattening than land-meat proteins, but the pathways involved are unclear. The team fed mice high-fat, high-protein diets built on casein, cod, or chicken. Some mice lived at room temperature and others at warmer thermoneutral conditions. The team then profiled blood lipids and gene activity in several tissues.
Protein source changed obesity development regardless of housing temperature, and each diet left a distinct fingerprint in blood lipids and in gene activity in liver and fat tissue. One-carbon metabolism, a network handling building blocks for DNA and other molecules, stood out as a likely affected pathway. A growth-control complex called mTOR emerged as a predicted upstream regulator tying the diet differences together.
Catalog record
| CREATOR | Lene S. Myrmel, Even Fjære, Annette Bernhard, Josef D. Rasinger, Ole Jakob Nøstbakken, Helene Søiland, Philipp Rausch, Martin von Bergen, Ulrike Rolle‐Kampzcyk, Liang Xiao, Hanlin Zhou, Guibo Li, Karsten Kristiansen, Lise Madsen |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 57 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |