Early multi-system physiological biomarkers of bronchopulmonary dysplasia in preterm infants: a matched case-control study based on bedside monitoring
Yu Ma, Jinhui Hu, Juan Liu, Yixin Zhang, Zhaojun Pan · 2026
Read Early multi-system physiological biomarkers of bronchopulmonary dysplasia in preterm infants: a matched case-control study based on bedside monitoring by Yu Ma, Jinhui Hu, Juan Liu, Yixin Zhang, Zhaojun Pan (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13454276.txt.
Description
Yu Ma and four co-authors hunt for early bedside signs of bronchopulmonary dysplasia, the chronic lung disease of very preterm babies. Their 2026 study matches 50 babies who developed the disease with 50 who did not. All were born before 32 weeks and cared for in one newborn unit between June 2022 and June 2025. Pairs were matched on pregnancy age and birth weight.
Six early measures predicted the disease together. They were use of a breathing machine, the peak oxygen share given, a falling perfusion trend, and a low oxygen ratio. Weaker heart pumping and a thinner heart wall measure completed the six. The combined model scored 0.982 on the standard curve, far above any single sign, which topped out at 0.864. At its best cut point it caught 93.47 percent of cases at 94.62 percent specificity. The authors offer the six sign profile for early risk sorting.
Catalog record
| CREATOR | Yu Ma, Jinhui Hu, Juan Liu, Yixin Zhang, Zhaojun Pan |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 36 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |