Compassionate-use of autologous, bone marrow–derived mesenchymal stromal cells in a chronic anoxic encephalopathy: a case report
Guilherme Lepski, Valeria Modestto, Walker Jeveaux, Daniel Navarro da Rocha, Roberto Dalto Fanganiello, Jose Ricardo Muniz Ferreira, Analia Arevalo · 2026
Read Compassionate-use of autologous, bone marrow–derived mesenchymal stromal cells in a chronic anoxic encephalopathy: a case report by Guilherme Lepski, Valeria Modestto, Walker Jeveaux, Daniel Navarro da Rocha, Roberto Dalto Fanganiello, Jose Ricardo Muniz Ferreira, Analia Arevalo (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13454205.txt.
Description
Guilherme Lepski and six co-authors report a compassionate use case of a patient's own bone marrow stem cells in long standing brain damage from oxygen loss. The patient, a young adult medical student, had lived with a disorder of consciousness after the injury. Their 2026 report works under national regulatory oversight, with cells grown under strict manufacturing and safety testing, then delivered into the spinal fluid.
Four months on, reviewers of video records scored the recovery scale at 11, up from 8 before treatment. Small gains showed in hearing, vision, and arousal, and the patient began a first repeatable yes no signal by blinking. Muscle stiffness eased a point in some groups, and no side effects appeared. Brain wave maps showed faster activity in front regions. The authors stress that one uncontrolled case cannot prove the cells worked.
Catalog record
| CREATOR | Guilherme Lepski, Valeria Modestto, Walker Jeveaux, Daniel Navarro da Rocha, Roberto Dalto Fanganiello, Jose Ricardo Muniz Ferreira, Analia Arevalo |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 30 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |