Emerging roles of cannabinoid pathways in renal injury and repair
Ricardo Romero-Guevara, Sergio Guzmán-Rodríguez, Bruno A. Marichal-Cancino · 2026
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Description
Ricardo Romero-Guevara, Sergio Guzmán-Rodríguez, and Bruno A Marichal-Cancino review how cannabis linked signaling paths affect kidney harm and healing. Their 2026 review starts from a hard fact: chronic kidney disease often ends in dialysis or transplant, both fraught with limits. The kidney carries two classic cannabinoid receptors, CB1 and CB2, plus several newer ones still being mapped.
Animal studies hint that tuning these receptors can slow kidney disease and blunt sudden kidney injury. The newer receptors, among them GPR55 and GPR18, have also shown links to kidney function. These paths cross talk with other receptor systems that govern blood pressure and pain. The authors frame the kidney's cannabinoid network as a field of open questions, with several drug targets worth testing.
Catalog record
| CREATOR | Ricardo Romero-Guevara, Sergio Guzmán-Rodríguez, Bruno A. Marichal-Cancino |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 56 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |