Real-world applicability of steatotic liver disease nomenclature: multifactorial phenotypes as an unmet classification need
Rosanna Villani, Elisabetta Cornacchia, Gaetano Serviddio · 2026
Read Real-world applicability of steatotic liver disease nomenclature: multifactorial phenotypes as an unmet classification need by Rosanna Villani, Elisabetta Cornacchia, Gaetano Serviddio (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13452784.txt.
Description
Rosanna Villani, Elisabetta Cornacchia and Gaetano Serviddio write to an editor about gaps in the 2023 naming system for steatotic liver disease. The consensus names cover metabolic disease, mixed metabolic and alcohol disease, and secondary causes. It grants that many causes can coexist, yet gives no working category for most combined cases.
The team applied the names to 1,414 adults sent to their liver unit from 2023 to 2025. Fatty liver was confirmed by ultrasound and a stiffness-based measure, and each case was checked for metabolic traits, alcohol use and secondary causes. Many real patients carried more than one driver at once. The letter argues that multi-cause forms are an unmet need in the classification.
Catalog record
| CREATOR | Rosanna Villani, Elisabetta Cornacchia, Gaetano Serviddio |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 9 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |