Plasma volume fraction in drug-resistant epilepsy: A DCE-MRI marker of microvascular pathology

Amirhossein Talebanpour, Sheida Mirloo, Alireza Aleali, Lyna Kamintsky, Yonatan Serlin, Nir Cafri, Ilan Goldberg, Chris Bowen, Gal Ben-Arie, Theodor Rüber, Felix Benninger, Ben Whatley, Alon Friedman · 2026

Read Plasma volume fraction in drug-resistant epilepsy: A DCE-MRI marker of microvascular pathology by Amirhossein Talebanpour, Sheida Mirloo, Alireza Aleali, Lyna Kamintsky, Yonatan Serlin, Nir Cafri, Ilan Goldberg, Chris Bowen, Gal Ben-Arie, Theodor Rüber, Felix Benninger, Ben Whatley, Alon Friedman (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13452395.txt.

Description

Amirhossein Talebanpour and a large team test a brain scan marker for drug resistant epilepsy, a form of the illness that drugs fail to control. Their 2026 paper uses a special MRI method that tracks injected dye as it moves through tiny brain vessels. The marker, called plasma volume fraction, shows how much of a brain region is blood plasma held in small vessels.

Scans came from 49 people with epilepsy and 68 healthy people at two sites. Those with epilepsy showed more abnormal marker values, most often at the front and side of the brain and in memory linked regions. Leaks across the blood brain barrier were common too, but pairing both measures made the odd spots stand out more sharply. A computer classifier told the two groups apart with fair skill, which hints the marker may help locate seizure zones.

Catalog record

CREATORAmirhossein Talebanpour, Sheida Mirloo, Alireza Aleali, Lyna Kamintsky, Yonatan Serlin, Nir Cafri, Ilan Goldberg, Chris Bowen, Gal Ben-Arie, Theodor Rüber, Felix Benninger, Ben Whatley, Alon Friedman
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE54 KB
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13452395

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