Anti-resorptive agents in neuroendocrine bone metastases – A systematic review
Marianne S Elston, Colin Chan Chui, Jade AU Tamatea, Ben Lawrence, Veronica Boyle · 2026
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Description
Marianne Elston and co-authors review in 2026 whether bone-sparing drugs help patients whose hormone-gland tumors have spread to bone. Such spread is common and brings breaks and pain, yet the drugs' role here was unmapped. Six databases were searched for studies of these drugs in well-grown tumors of this kind with bone spread.
From over 2,400 finds, only five past studies with 348 patients in all passed the screen, and their designs varied widely. One small study tied monthly drugs of one class to longer survival, three found no gap, and one found fewer bone events. Harm reports were patchy. The authors say proof is too thin and a forward trial is needed.
Catalog record
| CREATOR | Marianne S Elston, Colin Chan Chui, Jade AU Tamatea, Ben Lawrence, Veronica Boyle |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 24209 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |