tRF and gastric cancer: molecular mechanism exploration and novel strategies for precision diagnosis and therapy

Hongping Jia, Yiyao Duan, Yun Huang, Jun Hu, Xirui Fan, Rui Gong, Ningyan Zhang, Rong Qin, Hui Wang · 2026

Read tRF and gastric cancer: molecular mechanism exploration and novel strategies for precision diagnosis and therapy by Hongping Jia, Yiyao Duan, Yun Huang, Jun Hu, Xirui Fan, Rui Gong, Ningyan Zhang, Rong Qin, Hui Wang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13452128.txt.

Description

Hongping Jia and co-authors review in 2026 tiny RNA snips cut from carrier RNAs as new marks and tools against stomach cancer. Stomach cancer still kills heavily, and today's blood marks miss too much. The snips, called tRFs, are stable in body fluids and steer genes in ways that partly set them apart from their better-known microRNA kin.

Patient samples show tRF patterns that sort cancer with force past older marks, and the review names lead candidates. Yet the same snip can act in opposed ways, lab reads vary, and no trial has yet tested them in care. The authors call for shared lab rules and hard proof before clinics adopt the snips.

Catalog record

CREATORHongping Jia, Yiyao Duan, Yun Huang, Jun Hu, Xirui Fan, Rui Gong, Ningyan Zhang, Rong Qin, Hui Wang
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE39809
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13452128

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