Clinical Images: Bilateral eyelid swelling as the presenting feature of Sjögren's disease
Yu‐Chen Jeng, Chun‐Hsin Wu, Julia Yu‐Yun Lee, Sheng‐Chi Yang, Tak‐Wah Wong · 2026
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Description
Jeng and co-authors present a clinical image case of Sjögren's disease announced by swollen eyelids in this 2026 report. Their patient was a 52-year-old woman. She had a year of progressive swelling around both eyes, with redness and warmth. Dry eyes and a mildly dry mouth completed the picture. Sjögren's disease is an autoimmune condition that mainly dries the eyes and mouth, so eyelid swelling is an unusual first sign.
Blood tests showed inflammation, high antibody levels, and positive anti-SSA and anti-SSB antibodies, while a tear test confirmed severely reduced tear production, securing the diagnosis. A small eyelid biopsy showed dense immune-cell infiltration, and further checks excluded the look-alike condition IgG4-related disease as well as lymphoma. Treatment with prednisolone and hydroxychloroquine nearly resolved the swelling and redness by week twenty of care.
Catalog record
| CREATOR | Yu‐Chen Jeng, Chun‐Hsin Wu, Julia Yu‐Yun Lee, Sheng‐Chi Yang, Tak‐Wah Wong |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |