Predictors of treatment response to subthreshold micropulse laser and oral spironolactone therapy for central serous chorioretinopathy
Sheng Gao, Yun Zhang, Ge Ge, Meixia Zhang · 2026
Read Predictors of treatment response to subthreshold micropulse laser and oral spironolactone therapy for central serous chorioretinopathy by Sheng Gao, Yun Zhang, Ge Ge, Meixia Zhang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13450446.txt.
Description
Sheng Gao and colleagues searched for predictors of response to two treatments for central serous chorioretinopathy in 2026, a retina condition where fluid leaks under the retina and blurs vision. Options include subthreshold micropulse laser and oral spironolactone, but doctors lacked clear markers of who benefits from each. The team compared baseline traits and imaging measures.
One hundred three eyes from ninety-seven patients were split into a laser group of fifty-two eyes and a spironolactone group of fifty-one eyes. Fluid resolution and retinal thickness improved in both groups, while choroidal thickness fell only with spironolactone. Baseline fluid area predicted resolution in both groups, while other factors predicted change only with spironolactone. Clinicians gain a basis for matching patients to the treatment most likely to clear fluid.
Catalog record
| CREATOR | Sheng Gao, Yun Zhang, Ge Ge, Meixia Zhang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |