Thermally controlled microdroplet formation generated by fatty acid oil

Mitra Shojania Feizabadi, James W Paisnel, Jelena Stanisic · 2026

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Description

Mitra Shojania Feizabadi, James Paisnel, and Jelena Stanisic describe in 2026 a microfluidic method that forms droplets in fatty acid oil and steers their size with temperature. Droplet systems turn tiny volumes into isolated reaction chambers for cell and molecular work, yet the field leans on fluorinated oils now shadowed by concern over persistent PFAS chemicals. Emu oil, rich in unsaturated fatty acids, offers a more biologically familiar continuous phase, one the lead author's earlier work introduced as a new droplet class.

The team quantified how temperature shifts droplet size in this oil, giving users a dial rather than a fixed geometry. Working in a fatty acid medium at controlled, body-like temperatures also makes the droplets a more physiologically relevant stage for cellular analysis than harsh synthetic oils allow. The authors position phase-based thermal control as a greener, gentler route to droplet experiments in biochemistry and molecular biology.

Catalog record

CREATORMitra Shojania Feizabadi, James W Paisnel, Jelena Stanisic
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE20491
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13450001

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