Association of Time in Range and Time in Tight Range With Cardiovascular Risk Factor Exposure in Youth With Type 1 Diabetes: A Cross‐Sectional Analysis on LDL Cholesterol and Blood Pressure Data From the SWEET International Database
Claudia Piona, Agata Chobot, Jantje Weiskorn, Arun Shankar, Ingrida Stankute, Katrin Nagl, Marie‐Anne Burckhardt, Christina Kanaka‐Gantenbein, Francesco Gasparini, Marina Cavalin, Eva Hauser, Stefanie Lanzinger, Claudio Maffeis, SWEET Study Group · 2026
Read Association of Time in Range and Time in Tight Range With Cardiovascular Risk Factor Exposure in Youth With Type 1 Diabetes: A Cross‐Sectional Analysis on LDL Cholesterol and Blood Pressure Data From the SWEET International Database by Claudia Piona, Agata Chobot, Jantje Weiskorn, Arun Shankar, Ingrida Stankute, Katrin Nagl, Marie‐Anne Burckhardt, Christina Kanaka‐Gantenbein, Francesco Gasparini, Marina Cavalin, Eva Hauser, Stefanie Lanzinger, Claudio Maffeis, SWEET Study Group (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13448953.txt.
Description
Claudia Piona and colleagues use the international SWEET registry in 2026. They ask whether glucose sensor metrics in young people with type 1 diabetes relate to heart risk factors beyond the usual blood test. The analysis covered 3,328 patients aged 6 to 18 with at least a year of diabetes and at least fourteen days of sensor data, none on blood pressure or lipid drugs. Cholesterol and blood pressure were compared against time spent in target glucose ranges.
More time in range, and in the tighter range, went with lower LDL cholesterol and lower blood pressure scores, while time spent high pointed the other way. These links survived adjustments for sex, puberty, body size, and diabetes duration. Adding HbA1c weakened the blood pressure links, yet the cholesterol associations remained significant, though one model flipped their direction. The authors argue sensor metrics deserve a place beside HbA1c when judging cardiovascular risk in youth.
Catalog record
| CREATOR | Claudia Piona, Agata Chobot, Jantje Weiskorn, Arun Shankar, Ingrida Stankute, Katrin Nagl, Marie‐Anne Burckhardt, Christina Kanaka‐Gantenbein, Francesco Gasparini, Marina Cavalin, Eva Hauser, Stefanie Lanzinger, Claudio Maffeis, SWEET Study Group |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 48805 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |