Rare-Earth modified biodegradable Zn alloys with high strength and enhanced osteogenesis

Jiahui Shi, Mingyu Qu, Chaoyang Sun, Shuang Li, Jialian Xu, Ting Zhang, Xinhua Qu, Hongtao Yang, Yufeng Zheng · 2026

Read Rare-Earth modified biodegradable Zn alloys with high strength and enhanced osteogenesis by Jiahui Shi, Mingyu Qu, Chaoyang Sun, Shuang Li, Jialian Xu, Ting Zhang, Xinhua Qu, Hongtao Yang, Yufeng Zheng (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13448824.txt.

Description

Jiahui Shi and co-authors engineer in 2026 a zinc alloy meant to fix load-bearing bones and then dissolve once healing is done. Adding trace rare-earth elements to a zinc-lithium-manganese base created internal phases with a mixed grain structure. The resulting material reached a tensile strength of 772 megapascals and bending strength of 1,207 megapascals, close to medical titanium.

Those same phases even out the alloy's breakdown, releasing zinc ions at a controlled rate rather than in bursts. The tuned ion levels switched on the Rap1 signaling pathway in bone-forming cells. Implants of the alloy produced about twice as much new bone as titanium implants in the team's tests. The authors present the zinc-lithium-manganese-yttrium alloy as a degradable alternative to permanent metal fixation for demanding orthopedic repairs.

Catalog record

CREATORJiahui Shi, Mingyu Qu, Chaoyang Sun, Shuang Li, Jialian Xu, Ting Zhang, Xinhua Qu, Hongtao Yang, Yufeng Zheng
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE61424
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13448824

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