A Bioactive PLGA-modified SIS scaffold loaded with astragaloside IV–preconditioned BMSCs promotes infected wound healing
Xilai Hu, Yuhao Wu, Yaqian Chen, Xiaowen Li, Hai Huang · 2026
Read A Bioactive PLGA-modified SIS scaffold loaded with astragaloside IV–preconditioned BMSCs promotes infected wound healing by Xilai Hu, Yuhao Wu, Yaqian Chen, Xiaowen Li, Hai Huang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13447858.txt.
Description
Xilai Hu and coauthors develop a 2026 bioactive scaffold for sick wounds, joining PLGA-tweaked gut lining with stem cells primed by astragaloside IV. The team tested strength, cell conduct, and healing in vitro and in a sick wound model.
The scaffold boosted strength and backed stem cell sticking and growth, while priming boosted living and healing signals VEGF and TGF-beta. In animals, treated wounds closed faster with less swelling, about 50 percent more fiber, thicker new skin, more vessels, and calmer signals. The multi-use design holds out better chronic wound care, pending medical trials.
Catalog record
| CREATOR | Xilai Hu, Yuhao Wu, Yaqian Chen, Xiaowen Li, Hai Huang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 38 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |