Loss of the nuclear factor Y subunit B3 gene causes chlorosis and chloroplast development defects in cucumber
Min Sheng, Siqi Wang, Tiefeng Song, Juyong Zhao, Cancan Xia, Huanle He, Junsong Pan, Jian Pan, Haifan Wen · 2026
Read Loss of the nuclear factor Y subunit B3 gene causes chlorosis and chloroplast development defects in cucumber by Min Sheng, Siqi Wang, Tiefeng Song, Juyong Zhao, Cancan Xia, Huanle He, Junsong Pan, Jian Pan, Haifan Wen (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13446120.txt.
Description
Min Sheng and eight co-authors trace a cucumber mutant's yellow, dying seedlings to a broken transcription factor, in this 2026 study. The mutant, found through map based cloning, carries a jumping gene insertion in the gene for a factor called NF-YB3. Without it, seedlings make far less chlorophyll and photosynthesize weakly, and their chloroplasts grow stunted with underbuilt internal membranes.
Deleting the gene with CRISPR editing reproduced the defect, confirming the culprit. The factor partners with a sister subunit and switches on a gene for importing proteins into chloroplasts. It is most active in young tissues and rises with light. Genome wide expression in the mutant showed photosynthesis genes broadly turned down. The authors establish the factor as a core requirement for building chloroplasts in cucumber.
Catalog record
| CREATOR | Min Sheng, Siqi Wang, Tiefeng Song, Juyong Zhao, Cancan Xia, Huanle He, Junsong Pan, Jian Pan, Haifan Wen |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 44 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |