Prenatal and/or childhood acid-suppressive medication use and risk of serious infections in children: A retrospective analysis of Taiwanese medical claims data

Tsung-Chieh Yao, Yu-Lung Hsu, Jing-Long Huang, Yen-Chen Chang, Sheng-Mao Chang, Jen-Jung Pan, Xiumei Hong, Jiu-Yao Wang, Hui-Ju Tsai · 2026

Read Prenatal and/or childhood acid-suppressive medication use and risk of serious infections in children: A retrospective analysis of Taiwanese medical claims data by Tsung-Chieh Yao, Yu-Lung Hsu, Jing-Long Huang, Yen-Chen Chang, Sheng-Mao Chang, Jen-Jung Pan, Xiumei Hong, Jiu-Yao Wang, Hui-Ju Tsai (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13445769.txt.

Description

Tsung-Chieh Yao and coauthors report a 2026 Taiwan claims study of whether acid-cutting drugs while expecting or in childhood raise serious illness risk in children. The team set pre-birth and childhood contact with proton pump blockers or H2 blockers against antacid contact, tracking hospital stays for illnesses with tuned hazard models.

Pre-birth contact linked to a modest overall illness rise, including sepsis, bronchitis, pneumonia, gastroenteritis, and kidney illness. Childhood contact also raised risks, with the highest risks in children exposed in both periods, including a steep sepsis signal. Doctors should weigh illness risk when giving these common drugs to mothers and young children.

Catalog record

CREATORTsung-Chieh Yao, Yu-Lung Hsu, Jing-Long Huang, Yen-Chen Chang, Sheng-Mao Chang, Jen-Jung Pan, Xiumei Hong, Jiu-Yao Wang, Hui-Ju Tsai
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE43 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13445769

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