Immunological biomarkers for precision stereotactic body radiation therapy in early-stage non-small cell lung cancer: a systematic review

Stefania Volpe, Seungju Lee, Mateusz Bilski, Maria Giulia Vincini, Michela Onza, Gaia Piperno, Maria Alessia Zerella, Luigi Cornacchia, Lucia Palumbo, Paola Fulghieri, Alfonso Zappia, Roberta Noberini, Mariano Lombardi, Eltjona Mane, Konstantinos Venetis, Monica Casiraghi, Lorenzo Spaggiari, Tiziana Bonaldi, Nicola Fusco, Roberto Orecchia, Barbara Alicja Jereczek-Fossa · 2026

Read Immunological biomarkers for precision stereotactic body radiation therapy in early-stage non-small cell lung cancer: a systematic review by Stefania Volpe, Seungju Lee, Mateusz Bilski, Maria Giulia Vincini, Michela Onza, Gaia Piperno, Maria Alessia Zerella, Luigi Cornacchia, Lucia Palumbo, Paola Fulghieri, Alfonso Zappia, Roberta Noberini, Mariano Lombardi, Eltjona Mane, Konstantinos Venetis, Monica Casiraghi, Lorenzo Spaggiari, Tiziana Bonaldi, Nicola Fusco, Roberto Orecchia, Barbara Alicja Jereczek-Fossa (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13443911.txt.

Description

Stefania Volpe and colleagues review immune marks that may guide focused radiation for early lung cancer in a 2026 paper. The radiation style, SBRT, kills small tumors without cuts, yet results swing between patients. Marks that foretell control or return could steer who needs more care.

Four databases plus trial lists were screened in November 2025 for mark-outcome links in stage I to II disease. Studies clashed so much in marks, outcome picks, and math that no pooled count or grade pass was fair. Immune therapy now joins this field, which raises the stakes for good marks. The authors map what each study found and where proof thins. They call for shared mark lists and outcome terms so trials can add up.

Catalog record

CREATORStefania Volpe, Seungju Lee, Mateusz Bilski, Maria Giulia Vincini, Michela Onza, Gaia Piperno, Maria Alessia Zerella, Luigi Cornacchia, Lucia Palumbo, Paola Fulghieri, Alfonso Zappia, Roberta Noberini, Mariano Lombardi, Eltjona Mane, Konstantinos Venetis, Monica Casiraghi, Lorenzo Spaggiari, Tiziana Bonaldi, Nicola Fusco, Roberto Orecchia, Barbara Alicja Jereczek-Fossa
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE50713
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13443911

Browse the full library · About the Tower of Babel