Comparing Early Graft Dysfunction Scores in Liver Transplantation After Ex‐Situ Normothermic Machine Perfusion
Kejal Shah, Sydney Castellanos, April J Logan, Leonid Gorelik, Annelise Nolan, Manoj Iyer, Lauren Von Stein, Wei Chen, Ayato Obana, Ashley Limkemann, Navdeep Singh, Sylvester Black, William K Washburn, Austin D Schenk, Musab Alebrahim, Sai Rithin Punjala · 2026
Read Comparing Early Graft Dysfunction Scores in Liver Transplantation After Ex‐Situ Normothermic Machine Perfusion by Kejal Shah, Sydney Castellanos, April J Logan, Leonid Gorelik, Annelise Nolan, Manoj Iyer, Lauren Von Stein, Wei Chen, Ayato Obana, Ashley Limkemann, Navdeep Singh, Sylvester Black, William K Washburn, Austin D Schenk, Musab Alebrahim, Sai Rithin Punjala (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13439351.txt.
Description
Shah and colleagues ask which early warning scores still work for liver transplants kept on a warm perfusion machine. Machine perfusion holds the organ near body state, which may break scores built in the cold storage era. Their 2026 study reviews 126 perfused livers from 2022 to 2024. Seven judged unusable were set aside. Three scores were checked against survival in the 107 livers transplanted.
Two trajectory based scores failed to predict early graft loss at all. The simpler early dysfunction label did. It flagged 40 percent of grafts. Those livers had lower six month survival than the rest, 89 percent against 100 percent. Donor body weight, longer dying and sewing times, and weak pump readings, such as slow lactate clearing, tracked with dysfunction. Some livers past pump cutoffs still did well, so scores should guide, not dictate, organ use.
Catalog record
| CREATOR | Kejal Shah, Sydney Castellanos, April J Logan, Leonid Gorelik, Annelise Nolan, Manoj Iyer, Lauren Von Stein, Wei Chen, Ayato Obana, Ashley Limkemann, Navdeep Singh, Sylvester Black, William K Washburn, Austin D Schenk, Musab Alebrahim, Sai Rithin Punjala |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 43 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |