Association Between Chikungunya Infection and Rheumatoid Arthritis in Taiwan—A Cross‐Sectional Study
Chang‐Yi Yen, Chang‐Chi Lin, Ping‐Chang Lin, Ching‐Yi Tsai, Li‐Teh Liu, Chen‐Hsuan Lin, Chun‐Hong Chen, Chia‐Chun Tseng, Hua‐Chen Chan, Cheng‐Chin Wu, Tsan‐Teng Ou, Jih‐Jin Tsai, Jeng‐Hsien Yen · 2026
Read Association Between Chikungunya Infection and Rheumatoid Arthritis in Taiwan—A Cross‐Sectional Study by Chang‐Yi Yen, Chang‐Chi Lin, Ping‐Chang Lin, Ching‐Yi Tsai, Li‐Teh Liu, Chen‐Hsuan Lin, Chun‐Hong Chen, Chia‐Chun Tseng, Hua‐Chen Chan, Cheng‐Chin Wu, Tsan‐Teng Ou, Jih‐Jin Tsai, Jeng‐Hsien Yen (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13439349.txt.
Description
Yen and colleagues test whether a mosquito-borne virus could be linked to rheumatoid arthritis in Taiwan in this 2026 cross-sectional study. Chikungunya virus can cause chronic joint inflammation resembling rheumatoid arthritis. That resemblance raises a question: does the virus help trigger the autoimmune disease itself? The team tested blood from 98 arthritis patients and 200 healthy controls with two commercial antibody kits and a laboratory neutralization assay.
Neutralizing antibodies, the most specific sign of past infection, appeared in two arthritis patients and in no controls, a difference that reached significance on one statistical test but not another. The commercial kits agreed poorly with the neutralization assay and with each other, in some comparisons no better than chance. The authors conclude the study was too small to establish any causal link and warn that the available serology tests are unreliable for this question.
Catalog record
| CREATOR | Chang‐Yi Yen, Chang‐Chi Lin, Ping‐Chang Lin, Ching‐Yi Tsai, Li‐Teh Liu, Chen‐Hsuan Lin, Chun‐Hong Chen, Chia‐Chun Tseng, Hua‐Chen Chan, Cheng‐Chin Wu, Tsan‐Teng Ou, Jih‐Jin Tsai, Jeng‐Hsien Yen |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 22 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |