A natural variation in rice susceptibility factor Rsf1 confers resistance to root-knot nematode

Jingwen Yu, Chao Xiang, Deliang Peng, Huan Peng, Shiming Liu, Lingan Kong, Ling Qing, Mingjun Li, Xiyue Yu, Huanhuan Hao, Yaqin Liu, Wencui Wu, Xue Han, Yanxue Chen, Houxiang Kang, Wenkun Huang · 2026

Read A natural variation in rice susceptibility factor Rsf1 confers resistance to root-knot nematode by Jingwen Yu, Chao Xiang, Deliang Peng, Huan Peng, Shiming Liu, Lingan Kong, Ling Qing, Mingjun Li, Xiyue Yu, Huanhuan Hao, Yaqin Liu, Wencui Wu, Xue Han, Yanxue Chen, Houxiang Kang, Wenkun Huang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13439190.txt.

Description

Jingwen Yu and a large team hunt for rice genes that leave plants open to root-knot worms, publishing their findings in 2026. The worm Meloidogyne graminicola bores into rice roots and cuts yields across Asia, yet few resistant rice types are known. Genome-wide scans, multi-layer molecular data, and gene tests pointed to a factor named Rsf1, which codes a small cysteine-rich protein. A single letter change in the gene's switch region separated types by risk.

Plants with the risky letter made much more Rsf1 once worms attacked, while the safer letter kept levels low and plants held up better. A regulator called Myb44 was shown to drive Rsf1 output. Knocking the gene out in rice and in a model weed both raised resistance, pointing to a shared weakness that breeders could target.

Catalog record

CREATORJingwen Yu, Chao Xiang, Deliang Peng, Huan Peng, Shiming Liu, Lingan Kong, Ling Qing, Mingjun Li, Xiyue Yu, Huanhuan Hao, Yaqin Liu, Wencui Wu, Xue Han, Yanxue Chen, Houxiang Kang, Wenkun Huang
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE57847
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13439190

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