The impacts of native potential probiotic cocktail to prevent or ameliorate inflammation by targeting autophagy signalling pathway
Fatemeh Haririzadeh Jouriani, Mahdi Torkamaneh, Mahnaz Torfeh, Amin Sepehr, Fatemeh Ashrafian, Shadi Aghamohammad, Mahdi Rohani · 2026
Read The impacts of native potential probiotic cocktail to prevent or ameliorate inflammation by targeting autophagy signalling pathway by Fatemeh Haririzadeh Jouriani, Mahdi Torkamaneh, Mahnaz Torfeh, Amin Sepehr, Fatemeh Ashrafian, Shadi Aghamohammad, Mahdi Rohani (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13439022.txt.
Description
Fatemeh Haririzadeh Jouriani and colleagues tested whether a cocktail of local probiotic bacteria can switch on the cell-cleaning program that calms gut inflammation. Autophagy, the process by which cells digest damaged parts, is entangled with inflammatory bowel disease. Their 2026 study used a human intestinal cell line, inflaming it with broken-down pathogens and adding a native bacterial mixture before, during, or after the insult.
Gene measurements told a consistent story. The cocktail raised autophagy gene activity in every timing, strongest when the bacteria arrived before inflammation began. That ordering matters: prevention outperformed rescue. The authors conclude their native strains can influence the autophagy pathway and could serve a preventive role, at least in this dish-based model. Still, the result sketches a mechanism by which fermented-food bacteria might earn a place beside anti-inflammatory strategies.
Catalog record
| CREATOR | Fatemeh Haririzadeh Jouriani, Mahdi Torkamaneh, Mahnaz Torfeh, Amin Sepehr, Fatemeh Ashrafian, Shadi Aghamohammad, Mahdi Rohani |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35644 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |