Association between introduction of 13-valent pneumococcal conjugate vaccine and burden of hospitalized adult pneumococcal disease in Taiwan – a retrospective database study

Chi-Chuan Wang, Ting-An Yen, Jhong-Lin Wu, Ling-Ya Huang, See-Hwee Yeo, Dony Patel, Cindy Lim, Hung-Wei Lin, Eriko Yamada, Isaya Sukarom · 2026

Read Association between introduction of 13-valent pneumococcal conjugate vaccine and burden of hospitalized adult pneumococcal disease in Taiwan – a retrospective database study by Chi-Chuan Wang, Ting-An Yen, Jhong-Lin Wu, Ling-Ya Huang, See-Hwee Yeo, Dony Patel, Cindy Lim, Hung-Wei Lin, Eriko Yamada, Isaya Sukarom (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13437988.txt.

Description

Chi-Chuan Wang and colleagues measured whether adding a stronger pneumococcal vaccine to Taiwan's childhood program in 2015 also shielded adults, who catch the germ from children. Their 2026 study mined the national insurance database for adults hospitalized with invasive pneumococcal disease or pneumonia from 2011 to 2019. The team compared years before the change with years after, skipping the switch year.

Hospital rates for both illnesses stepped down after the childhood program began. Invasive disease fell to about three-quarters of its former level and pneumonia to about eighty-seven percent. A slow upward creep in rates inside the later window tempers the win, and the total burden stays substantial. The pattern fits herd protection: vaccinate toddlers, and grandparents land in hospital less often. Because the data are records rather than a trial, other forces, such as changing care habits, could share the credit.

Catalog record

CREATORChi-Chuan Wang, Ting-An Yen, Jhong-Lin Wu, Ling-Ya Huang, See-Hwee Yeo, Dony Patel, Cindy Lim, Hung-Wei Lin, Eriko Yamada, Isaya Sukarom
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE50611
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13437988

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