Non-femoral head MRI radiomics as a potential imaging biomarker for identifying osteonecrosis of the femoral head in systemic lupus erythematosus patients
Yujing Zhang, Qing Hou, Shasha Zheng, Xinwen Wang, Xiaoli Song, Wenjin Bian, Jianing Cui, Jinliang Niu · 2026
Read Non-femoral head MRI radiomics as a potential imaging biomarker for identifying osteonecrosis of the femoral head in systemic lupus erythematosus patients by Yujing Zhang, Qing Hou, Shasha Zheng, Xinwen Wang, Xiaoli Song, Wenjin Bian, Jianing Cui, Jinliang Niu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13437393.txt.
Description
Yujing Zhang and colleagues tested an unusual idea: signs of hip bone death in lupus might show up in nearby bone that still looks healthy. Osteonecrosis of the femoral head, where the ball of the hip dies from poor blood flow, strikes many people with lupus. Their 2026 study mined MRI texture features, called radiomics, from the greater trochanter and the ilium rather than the hip ball itself, in 123 patients at one hospital and forty-four at another.
A model blending the texture features with clinical facts sorted patients well in training and held up in both check groups, though it faded in outside data. The texture-only model proved steadier, and adding clinical facts did not clearly help. They call the signals a possible early marker, not a test ready for use. Prospective studies, they say, must confirm that healthy-looking bone really carries a readable warning of damage nearby.
Catalog record
| CREATOR | Yujing Zhang, Qing Hou, Shasha Zheng, Xinwen Wang, Xiaoli Song, Wenjin Bian, Jianing Cui, Jinliang Niu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 38041 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |