Ketamine-Assisted Psychotherapy for Posttraumatic Stress Disorder: A Systematic Review and Individual Participant Data Meta-Analysis of Predictors of Treatment Effects
Judith Rohde, Tyler M. Moore, Kathryn Walker, Shobi S. Ahmed, Henry A. MacConnel, Martin Krsak, Scott Shannon, Vivian W.L. Tsang, Shannon Dames, Marco Buchmann, Birgit Kleim, Erich Seifritz, Sebastian Olbrich, Georgios Schoretsanitis · 2026
Read Ketamine-Assisted Psychotherapy for Posttraumatic Stress Disorder: A Systematic Review and Individual Participant Data Meta-Analysis of Predictors of Treatment Effects by Judith Rohde, Tyler M. Moore, Kathryn Walker, Shobi S. Ahmed, Henry A. MacConnel, Martin Krsak, Scott Shannon, Vivian W.L. Tsang, Shannon Dames, Marco Buchmann, Birgit Kleim, Erich Seifritz, Sebastian Olbrich, Georgios Schoretsanitis (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13436927.txt.
Description
Judith Rohde led a large team that pooled patient-level data from past trials of ketamine paired with talk therapy for posttraumatic stress disorder. Published in 2026, their review asked which patients gain most from the combined treatment and which parts of the care plan matter. Twelve studies with 533 adults took part, and symptom change was tracked with a standard checklist for the disorder.
People who started with worse symptoms improved the most, the team found. More therapy sessions and more ketamine sessions each linked to greater gains, and shorter overall treatment also linked to better results. Those patterns held for both men and women. Yet nine of the twelve studies were judged poor in quality, and in a smaller check using only stronger studies, starting severity was the sole clear predictor. The authors call for better trials with shared methods and longer follow-up before firm rules are set.
Catalog record
| CREATOR | Judith Rohde, Tyler M. Moore, Kathryn Walker, Shobi S. Ahmed, Henry A. MacConnel, Martin Krsak, Scott Shannon, Vivian W.L. Tsang, Shannon Dames, Marco Buchmann, Birgit Kleim, Erich Seifritz, Sebastian Olbrich, Georgios Schoretsanitis |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 39896 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |