Immune evasion, infectivity, and membrane fusion of SARS-CoV-2 variants LP.8.1.1, XEC.25.1, XFG, and NB.1.8.1
Feng Jiang, Miao Zheng, Long Gao, Yanhang Zhuo, Xiaoqin Liang, Zhiwei Chen, Xinghua Huang, Yisheng Chen, Zhaonan Zeng, Yufan Xiao, Xiaohong Du, Frank Xiao‐Feng Qin, Weihua Liu, Haijun Tang · 2026
Read Immune evasion, infectivity, and membrane fusion of SARS-CoV-2 variants LP.8.1.1, XEC.25.1, XFG, and NB.1.8.1 by Feng Jiang, Miao Zheng, Long Gao, Yanhang Zhuo, Xiaoqin Liang, Zhiwei Chen, Xinghua Huang, Yisheng Chen, Zhaonan Zeng, Yufan Xiao, Xiaohong Du, Frank Xiao‐Feng Qin, Weihua Liu, Haijun Tang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13436279.txt.
Description
Feng Jiang and a large team grade five coronavirus variants descended from the JN lineage for entry skill and immune escape in 2026. Cell tests weigh infection rates, receptor grip, and membrane fusion for each variant. Blood serum from prior cases tests how well antibodies still block them.
Two of the variants infect cells far better than their kin. One grips the ACE2 receptor tightest, while the other fuses membranes best in key cells. All five dodge antibodies better than the parent strain. All still enter cells bearing animal versions of the receptor. Vaccine updates should track this fast moving family.
Catalog record
| CREATOR | Feng Jiang, Miao Zheng, Long Gao, Yanhang Zhuo, Xiaoqin Liang, Zhiwei Chen, Xinghua Huang, Yisheng Chen, Zhaonan Zeng, Yufan Xiao, Xiaohong Du, Frank Xiao‐Feng Qin, Weihua Liu, Haijun Tang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 40408 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |