Genomic characterization of the type VI secretion system in extraintestinal pathogenic Escherichia coli

Julia Ienes-Lima, Sonsiray Álvarez-Narváez, Nicolle Lima Barbieri, Klao Runcharoon, Catherine M. Logue · 2026

Read Genomic characterization of the type VI secretion system in extraintestinal pathogenic Escherichia coli by Julia Ienes-Lima, Sonsiray Álvarez-Narváez, Nicolle Lima Barbieri, Klao Runcharoon, Catherine M. Logue (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13436143.txt.

Description

Julia Ienes-Lima and coauthors survey a needle like weapon across 399 genomes of gut escaping E coli in 2026. These strains cause urine, blood, and newborn brain infections in people and birds. The weapon, a type six secretion system, stabs rival cells and host cells alike.

The weapon shows most in newborn meningitis strains. Its layout matches bird strains closely, while blood and urine strains vary more. Strains with the weapon tend to carry less drug resistance, which hints at a fitness trade off. Evolution pressures differ by infection niche, the pattern suggests. Lab work must now test when the weapon fires.

Catalog record

CREATORJulia Ienes-Lima, Sonsiray Álvarez-Narváez, Nicolle Lima Barbieri, Klao Runcharoon, Catherine M. Logue
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE42538
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13436143

Browse the full library · About the Tower of Babel