Anti-tumor necrosis factor-α therapy and paradoxical autoimmunity in inflammatory bowel disease: a need for risk-aware monitoring

Ji Eun Kim · 2026

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Description

Ji Eun Kim discusses a paradox of bowel disease therapy in 2026: drugs that block a key swelling signal can spark fresh immune illness. A Korean study using national health records links the drugs to new cases of psoriasis and lung tissue disease. Risk rose soon after exposure began, then leveled off.

Skin change in the form of psoriasis is the most often reported twist. The piece links the effect to a shift in immune balance toward other pathways. Early onset hints that some patients carry the risk from the start. Clinicians are urged to watch skin and lungs closely in the first months of therapy.

Catalog record

CREATORJi Eun Kim
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE5 KB
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13434515

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