Structural insights into PSL polysaccharide assembly and export to the cell surface via the Wzx/Wzy-dependent pathway
Jiao Liu, Yanlong Han, Lanxin Wang, Luyan Z Ma, Dongchun Ni, Yihua Huang · 2026
Read Structural insights into PSL polysaccharide assembly and export to the cell surface via the Wzx/Wzy-dependent pathway by Jiao Liu, Yanlong Han, Lanxin Wang, Luyan Z Ma, Dongchun Ni, Yihua Huang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13434223.txt.
Description
Jiao Liu and colleagues map in 2026 how a germ builds and exports Psl, a sugar coat that helps it form sticky films on surfaces. The germ is Pseudomonas aeruginosa, a common cause of hard to treat lung illness. The sugar coat moves out through a guarded path that spans the cell wall.
Cryo electron images of two linked proteins show a sealed channel from inside to outside the cell. A third protein likely sits in the channel and links sugar units one by one. Side ports may feed new units in while the chain grows. The model may fit many germs that use the same export route.
Catalog record
| CREATOR | Jiao Liu, Yanlong Han, Lanxin Wang, Luyan Z Ma, Dongchun Ni, Yihua Huang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 49648 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |