Hydration control in molecular salts through counterion selection
Henry A. Holleb, Natalie E. Pridmore, Amy V. Hall, Pablo Martinez-Bulit, Aurora J. Cruz-Cabeza · 2026
Read Hydration control in molecular salts through counterion selection by Henry A. Holleb, Natalie E. Pridmore, Amy V. Hall, Pablo Martinez-Bulit, Aurora J. Cruz-Cabeza (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13434127.txt.
Description
Henry A Holleb and co-authors cracked a crystal puzzle in 2026. Some drug salts drink water into their crystals while kin salts stay dry. The split pins on how spread the partner ion's charge runs. Wet crystals can wreck a drug's shelf life and punch, yet calls on which salts turn wet have long missed. The team read more than thirty-one thousand crystal frames and ran charge math.
Spread charge on the partner ion chokes wet turns, while tight, pooled charge feeds them. That one knob swings wet odds from near four in five to under one in ten. Guided by the rule and an acid gap check, the team steered a test drug's salts to wet or dry forms on call. Salt pick thus turns a design dial, not a dice throw.
Catalog record
| CREATOR | Henry A. Holleb, Natalie E. Pridmore, Amy V. Hall, Pablo Martinez-Bulit, Aurora J. Cruz-Cabeza |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 60807 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |