Controlled delivery of nilotinib using LDH/Fe2O3-modified chitosan nanocomposite hydrogel beads for the treatment of chronic myeloid leukemia
Milad Gholami, Hori Ghaneialvar, Somayeh Molaei, Naser Abbasi, Ali Aidy, Mahsa Abbasi · 2026
Read Controlled delivery of nilotinib using LDH/Fe2O3-modified chitosan nanocomposite hydrogel beads for the treatment of chronic myeloid leukemia by Milad Gholami, Hori Ghaneialvar, Somayeh Molaei, Naser Abbasi, Ali Aidy, Mahsa Abbasi (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13433789.txt.
Description
Milad Gholami and co-authors packed a blood cancer drug in 2026 into gel beads of shell sugar laced with clay-like sheets and iron grains, aiming for slow, aimed release. The drug blocks a growth switch in a long-run white cell cancer. Stock dosing often spills the drug wide and fades fast, which caps its punch.
Beads formed in a warm, stirred bath, and scope plus ray reads proved the grains sat well in a holed gel web. Two load paths faced off: drug mixed in as beads formed, or soaked into dried beads after. Soak loads at a set share freed the most drug by six hours. The beads killed four cancer cell lines in dose steps while sparing vein wall cells, and they showed guard work against harsh oxygen scraps.
Catalog record
| CREATOR | Milad Gholami, Hori Ghaneialvar, Somayeh Molaei, Naser Abbasi, Ali Aidy, Mahsa Abbasi |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 36542 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |