Small interfering RNA (siRNA)-based targeting breast cancer therapy

Amin Talebi, Afshin Khorrami, Farshid Oruji, Shima Shabani, Saba Hajazimian, Hadi Nasiri, Soolmaz Khansalar, Alireza Isazadeh, Morteza Akbari · 2026

Read Small interfering RNA (siRNA)-based targeting breast cancer therapy by Amin Talebi, Afshin Khorrami, Farshid Oruji, Shima Shabani, Saba Hajazimian, Hadi Nasiri, Soolmaz Khansalar, Alireza Isazadeh, Morteza Akbari (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13433695.txt.

Description

Amin Talebi and colleagues review small interfering RNA therapy for breast cancer, a gene-silencing approach that targets cancer-driving genes. Breast cancer's global burden demands new treatments, and siRNA can selectively switch off genes behind tumour start and growth.

The review walks through how siRNA works at the molecular level, what it can target, and where its promise and pitfalls lie. A central theme is delivery: siRNA only helps if it reaches tumour cells intact and in sufficient dose. Clinicians and researchers get a balanced map of a precise but delivery-limited therapy, with targeting strategies that may one day make it routine.

Catalog record

CREATORAmin Talebi, Afshin Khorrami, Farshid Oruji, Shima Shabani, Saba Hajazimian, Hadi Nasiri, Soolmaz Khansalar, Alireza Isazadeh, Morteza Akbari
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE58 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13433695

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