In Vitro Metabolism of Δ8‐, Δ9‐, and Δ10‐THC in Human Hepatocytes: Distinct Δ10‐THC Biotransformation and Implications for Drug Testing
Robert Kronstrand, Henrik Green, Markus Loh, Fabian Rüttimann, Manuela Carla Monti · 2026
Read In Vitro Metabolism of Δ8‐, Δ9‐, and Δ10‐THC in Human Hepatocytes: Distinct Δ10‐THC Biotransformation and Implications for Drug Testing by Robert Kronstrand, Henrik Green, Markus Loh, Fabian Rüttimann, Manuela Carla Monti (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13432780.txt.
Description
Robert Kronstrand and colleagues test how three forms of THC break down in human liver cells, a key point for drug tests. Delta-9 THC is the main mind drug in cannabis and is tested a lot in clinics and courts, while delta-8 and delta-10 now sell in loosely ruled markets.
Since the three forms look much alike, tests can mix them up and misread results. Liver cells plus high-end liquid tests showed delta-8 breaking down much like delta-9, with hydroxy and carboxy forms plus their sugar-linked forms. Delta-10 broke down in its own way, with heavy sugar-linking. Test labs must heed that split, or they risk false calls about which form a person took.
Catalog record
| CREATOR | Robert Kronstrand, Henrik Green, Markus Loh, Fabian Rüttimann, Manuela Carla Monti |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 30 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |