Investigation of the In Vitro and In Vivo Metabolism and μ‐Opioid Receptor Affinity of the Nitazene N‐Pyrrolidino Fluetonitazene
Severin Zemp, Gaia Alluisetti, Wolfgang Weinmann, Bettina Schrag, Frank Sporkert, Maurine Leclerc, Katharina Elisabeth Grafinger · 2026
Read Investigation of the In Vitro and In Vivo Metabolism and μ‐Opioid Receptor Affinity of the Nitazene N‐Pyrrolidino Fluetonitazene by Severin Zemp, Gaia Alluisetti, Wolfgang Weinmann, Bettina Schrag, Frank Sporkert, Maurine Leclerc, Katharina Elisabeth Grafinger (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13432772.txt.
Description
Severin Zemp and colleagues study a new man-made opioid, N-pyrrolidino fluetonitazene, also known as fluetonitazepyne. Nitazenes are a fast-growing set of new mind drugs, and this one is a fluorine-tweaked cousin of etonitazepyne.
The team tracked how the drug breaks down in pooled human liver bits in the lab, and in true samples from a forensic case after death. High-end mass tests mapped the break-down products, while a second mass test confirmed and roughly measured the drug in urine and blood. A binding test then gauged how hard it grips the mu-opioid dock, the main pain-killing dock in the brain. Crime labs get the break-down map they need to spot this strong opioid.
Catalog record
| CREATOR | Severin Zemp, Gaia Alluisetti, Wolfgang Weinmann, Bettina Schrag, Frank Sporkert, Maurine Leclerc, Katharina Elisabeth Grafinger |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 61 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |