DNA‐Enzyme Hybrid Nanostructures: Functional Materials to Modulate Enzymatic Activity
Manar Elnaggar, Amelie Heuer‐Jungemann · 2026
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Description
Manar Elnaggar and Amelie Heuer-Jungemann reviewed in 2026 how tying enzymes to built DNA frames changes how fast those enzymes work. DNA craft can fold strands into exact flat and solid shapes. Pinning enzymes to such frames sets their place and count with rare care, which often lifts their pace past free work.
Past guesses for the lift lean on closeness, charge pull, and local acid shifts, yet none fully fits the reads. Shielding from wear helps too, and a held water skin may add more. Chain reactions with mismatched speeds gain little from closeness alone. Outsize enzymes strain the frames as well. The review maps the gaps and points to uses in green chemistry and built cells, with key puzzles still open.
Catalog record
| CREATOR | Manar Elnaggar, Amelie Heuer‐Jungemann |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 129269 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |