Immunogenicity of Human Papillomavirus Virus Vaccine in a High-risk and Understudied Group: Female Sex Workers
Nguyen Van Trang, Le Anh Tuan, Chu Thi Ngoc Mai, Le Thi Khanh Ly, Tran Hoang My Lien, Nguyen Thanh Chung, Dao Thi Thanh Huyen, Nguyen Thi To Uyen, Nham Thi Tuyen Thanh, Tran Thi Hong Nhung, Chau Quang, Claire Von Mollendorf, Gerald Murray, Suzanne M Garland, Kathryn Bright, Paul V Licciardi, Kim Mulholland, Zheng Quan Toh · 2026
Read Immunogenicity of Human Papillomavirus Virus Vaccine in a High-risk and Understudied Group: Female Sex Workers by Nguyen Van Trang, Le Anh Tuan, Chu Thi Ngoc Mai, Le Thi Khanh Ly, Tran Hoang My Lien, Nguyen Thanh Chung, Dao Thi Thanh Huyen, Nguyen Thi To Uyen, Nham Thi Tuyen Thanh, Tran Thi Hong Nhung, Chau Quang, Claire Von Mollendorf, Gerald Murray, Suzanne M Garland, Kathryn Bright, Paul V Licciardi, Kim Mulholland, Zheng Quan Toh (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13431786.txt.
Description
Trang and colleagues ran a pilot study in Hai Phong, Vietnam in 2026 on how well the HPV vaccine works in female sex workers. This group faces four to ten times the usual infection risk yet is rarely studied for vaccine response. Sixty-three women aged 18 to 26 received three doses of the quadrivalent Gardasil vaccine, with swabs at entry and blood draws across seven months.
At entry, nearly three in ten women carried a high-risk HPV type and about one in ten carried the two types the vaccine targets most. After one dose, nine in ten women already had antibodies to HPV16, and by month seven every participant had antibodies to both HPV16 and HPV18. Women who started virus-free mounted higher antibody levels than those already infected. The authors say the vaccine is immunogenic in this group and call for effectiveness studies.
Catalog record
| CREATOR | Nguyen Van Trang, Le Anh Tuan, Chu Thi Ngoc Mai, Le Thi Khanh Ly, Tran Hoang My Lien, Nguyen Thanh Chung, Dao Thi Thanh Huyen, Nguyen Thi To Uyen, Nham Thi Tuyen Thanh, Tran Thi Hong Nhung, Chau Quang, Claire Von Mollendorf, Gerald Murray, Suzanne M Garland, Kathryn Bright, Paul V Licciardi, Kim Mulholland, Zheng Quan Toh |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 31 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |