The WHO Classification of Genetic Tumour Syndromes: Considerations for Genetics
Ian A. Cree, Mark J. Arends, Joseph D. Khoury, Erika R. E. Denton, Anthony J. Gill, Alexander J. Lazar, Ian M. Frayling, Stefan M. Pfister, Mark A. Rubin, Katia R. M. Leite, Raymond Dalgleish, Elspeth A. Bruford, Sharon E. Plon, Ada Hamosh, Michael Francis Walsh, Gabrielle Goldman‐Lévy, Harshima Wijesinghe, William D. Foulkes, Dilani Lokuhetty · 2026
Read The WHO Classification of Genetic Tumour Syndromes: Considerations for Genetics by Ian A. Cree, Mark J. Arends, Joseph D. Khoury, Erika R. E. Denton, Anthony J. Gill, Alexander J. Lazar, Ian M. Frayling, Stefan M. Pfister, Mark A. Rubin, Katia R. M. Leite, Raymond Dalgleish, Elspeth A. Bruford, Sharon E. Plon, Ada Hamosh, Michael Francis Walsh, Gabrielle Goldman‐Lévy, Harshima Wijesinghe, William D. Foulkes, Dilani Lokuhetty (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13431718.txt.
Description
Ian A Cree and a large panel set out in 2026 how the World Health Organization now sorts inherited syndromes that raise tumor risk into one shared scheme. Past tumor guides had tucked such syndromes into organ chapters as boards saw fit, with no system-wide frame. Case finding for these families now shapes watch plans, drug picks, and risk talks across many organs.
A chain of meetings settled on a ladder sorted first by the cell process harmed, then by the path involved, the named syndrome, and the gene faults at its root. Lead processes span growth signals, cell cycle brakes, DNA repair, and the caps that guard chromosome ends, among others. Sorting the scheme laid bare gaps in what is known. The frame gives labs worldwide one tongue for fresh finds as they land.
Catalog record
| CREATOR | Ian A. Cree, Mark J. Arends, Joseph D. Khoury, Erika R. E. Denton, Anthony J. Gill, Alexander J. Lazar, Ian M. Frayling, Stefan M. Pfister, Mark A. Rubin, Katia R. M. Leite, Raymond Dalgleish, Elspeth A. Bruford, Sharon E. Plon, Ada Hamosh, Michael Francis Walsh, Gabrielle Goldman‐Lévy, Harshima Wijesinghe, William D. Foulkes, Dilani Lokuhetty |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 29500 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |