Infant Infection With Respiratory Syncytial Virus Genotypes and Subsequent Childhood Asthma Risk
Christian Rosas-Salazar, Tebeb Gebretsadik, James D Chappell, R Stokes Peebles, William D Dupont, Meghan H Shilts, Samadhan J Jadhao, Larry J Anderson, Suman R Das, Tina V Hartert · 2026
Read Infant Infection With Respiratory Syncytial Virus Genotypes and Subsequent Childhood Asthma Risk by Christian Rosas-Salazar, Tebeb Gebretsadik, James D Chappell, R Stokes Peebles, William D Dupont, Meghan H Shilts, Samadhan J Jadhao, Larry J Anderson, Suman R Das, Tina V Hartert (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13431657.txt.
Description
Rosas-Salazar and co-authors test whether the exact strain of a common infant virus shapes later asthma risk. Their 2026 paper uses a population-based birth cohort of healthy full-term children watched closely through their first virus season. The team focused on respiratory syncytial virus strains carrying duplications in the G gene, a viral surface gene suspected of changing how the virus behaves.
Children infected in infancy with duplication-carrying strains of either virus type had roughly double the odds of current asthma at age five compared with children who escaped infection in infancy. The adjusted odds were 2.00 for the A type and 1.78 for the B type carrying duplications. The authors call this proof-of-concept evidence that viral genetic variation, not just infection itself, is tied to different asthma risks. They frame strain typing as a possible route to predicting which infants need closer follow-up.
Catalog record
| CREATOR | Christian Rosas-Salazar, Tebeb Gebretsadik, James D Chappell, R Stokes Peebles, William D Dupont, Meghan H Shilts, Samadhan J Jadhao, Larry J Anderson, Suman R Das, Tina V Hartert |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 22 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |