Genetic diagnosis in fetuses with biliary tract system abnormalities: a meta-analysis and systematic review

Hanyu Cao, Yanping Qian, Zhu Zhang · 2026

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Description

Hanyu Cao and colleagues pool studies on genetic causes in fetuses with bile-duct system anomalies, rare findings with a wide range of outlooks. Knowing how often genes explain the anomaly, and which genes, shapes counselling and pregnancy planning.

PubMed and Ovid Medline were searched to June 2025 for studies reporting prenatal genetic results and outcomes. Pooled rates used random-effects models, split by isolated versus non-isolated cases, anomaly type, bile-duct pattern, test method, and abnormality class. The team also counted bile-duct blockage among fetuses with normal genetic results, giving fetal-medicine teams a firmer evidence base.

Catalog record

CREATORHanyu Cao, Yanping Qian, Zhu Zhang
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE41 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13430891

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