Prevalence, resistance profile of ESKAPEE pathogens, and molecular detection of PMQR-associated genes among Levofloxacin-resistant gram-negative ESKAPEE isolates from critically-ill patients
Sylvana Nady Gaber, Rasha H Bassyouni, Ahmed Ashraf Wegdan, Hagar Saad Abd-elrahman, Ahmed Fathy Elkhateeb, Joseph Makram Botros, Mahmoud A F Khalil, Hanaa Mohamed Eid Moawad · 2026
Read Prevalence, resistance profile of ESKAPEE pathogens, and molecular detection of PMQR-associated genes among Levofloxacin-resistant gram-negative ESKAPEE isolates from critically-ill patients by Sylvana Nady Gaber, Rasha H Bassyouni, Ahmed Ashraf Wegdan, Hagar Saad Abd-elrahman, Ahmed Fathy Elkhateeb, Joseph Makram Botros, Mahmoud A F Khalil, Hanaa Mohamed Eid Moawad (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13428415.txt.
Description
Gaber and colleagues surveyed drug-resistant hospital bacteria in 2026 among critically ill patients at Fayoum University Hospitals in Egypt. They focused on the ESKAPEE group, a set of germs notorious for escaping antibiotics, collected from August 2021 to July 2022. In levofloxacin-resistant strains they also hunted for mobile resistance genes that bacteria can pass to each other on small DNA rings.
Of eighty-four isolates grown from seventy-two patients, ninety-four percent were ESKAPEE organisms. Enterococcus faecium was commonest, and over three quarters of those strains resisted vancomycin, a last-line drug. Most Pseudomonas, E. coli, and Klebsiella isolates were extensively drug resistant, meaning almost no standard drugs still worked. The gene qnrB appeared in nearly seventy-nine percent of resistant strains tested, and most carried more than one such gene. The authors warn that resistance is spreading on mobile DNA in intensive care.
Catalog record
| CREATOR | Sylvana Nady Gaber, Rasha H Bassyouni, Ahmed Ashraf Wegdan, Hagar Saad Abd-elrahman, Ahmed Fathy Elkhateeb, Joseph Makram Botros, Mahmoud A F Khalil, Hanaa Mohamed Eid Moawad |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 31 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |