Real-World Comparative Effectiveness and Safety of Immune Checkpoint Inhibitors in Advanced Renal Cell Carcinoma: A Systematic Review
Chin Hang Yiu, Gwyneth Yuet Yin Leung, Isabelle C. Lee, Christine Y. Lu · 2026
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Description
Chin Hang Yiu and colleagues gather real-world evidence on immune checkpoint drugs as first treatment for advanced kidney cancer. These regimens are now standard, yet head-to-head results from daily practice, outside trials, remain patchy.
MEDLINE, Embase, and Scopus were searched to January 2026 under systematic-review reporting rules, taking observational cohorts with an active comparator. Overall survival, time without progression, and response rate were the efficacy outcomes, with treatment-related harms on the safety side. Oncologists get a synthesis of what these drugs do when patients are older, sicker, and less selected than trial volunteers.
Catalog record
| CREATOR | Chin Hang Yiu, Gwyneth Yuet Yin Leung, Isabelle C. Lee, Christine Y. Lu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 168 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |