Relationship between knowledge, adherence-related behaviors and self-management with response to monoclonal antibody therapy in patients with severe asthma
Christopher Alexander Hinze, Vincent Müller, Christina Valtin, Frederik Trinkmann, Katrin Milger, Nora Drick, Hendrik Suhling, Jan Fuge · 2026
Read Relationship between knowledge, adherence-related behaviors and self-management with response to monoclonal antibody therapy in patients with severe asthma by Christopher Alexander Hinze, Vincent Müller, Christina Valtin, Frederik Trinkmann, Katrin Milger, Nora Drick, Hendrik Suhling, Jan Fuge (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13427718.txt.
Description
Hinze and colleagues asked in 2026 what separates patients with severe eosinophilic asthma who answer antibody therapy well from those who do not, looking beyond the drug to knowledge and habits. Antibody drugs have changed severe asthma care, yet some patients stay uncontrolled. The team recruited patients on treatment at three German clinics.
Of 140 patients, about three in five were classed as responders, a quarter as partial, and the rest as non-responders, with lung measures alike across groups. Asthma knowledge differed clearly by response group and stayed linked to response after adjustment for other factors. General activation, how engaged patients feel in their care, did not predict response. A negative attitude toward medicines showed a weaker, uncertain link. The authors back teaching and adherence support tailored to each patient.
Catalog record
| CREATOR | Christopher Alexander Hinze, Vincent Müller, Christina Valtin, Frederik Trinkmann, Katrin Milger, Nora Drick, Hendrik Suhling, Jan Fuge |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 37 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |