Neurophysiological Characteristics of Nitrous Oxide‐Induced Polyneuropathy: A Case Series

Tanya Elisabeth Bentley, Volker Limmroth, Maximilian Zimmermann, Johannes Fabian Holle · 2026

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Description

Tanya Bentley and co-authors describe nerve damage from laughing gas misuse in a 2026 case series. Recreational nitrous oxide use is rising across Europe, and the nerve injury it causes can leave lasting deficits. The team reviews twelve patients with acute symptoms and a history of abuse who had electrical nerve testing at a German hospital.

Eight of the twelve show nerve damage, most often a pure motor pattern, and no distinct symptom profile marks them out. A spinal signal test was abnormal in every assessable patient. Only three of ten tested had low vitamin B12, yet all showed high levels of a related acid, which the authors call the more reliable marker.

Catalog record

CREATORTanya Elisabeth Bentley, Volker Limmroth, Maximilian Zimmermann, Johannes Fabian Holle
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE27 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13427618

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