Immunophenotype and proviral landscape of HTLV-1c infection and pulmonary disease
Ashley Hirons, Natasha Jansz, Georges Khoury, Paula Ellenberg, Sarah Collins, James Cooney, John Zaunders, Lewis Williams, Kirthi Nandha Nair, Ashley Huey Yiing Yap, Nicholas Hirons, Liana Mackiewicz, Merle Dayton, Le Wang, Daniel Sijmons, Mohammad Radwanur Talukder, Allegra Holloway Vickas, Amy W. Chung, Marcel Doerflinger, Marc Pellegrini, Lloyd Einsiedel, Geoffrey Faulkner, Damian F.J. Purcell · 2026
Read Immunophenotype and proviral landscape of HTLV-1c infection and pulmonary disease by Ashley Hirons, Natasha Jansz, Georges Khoury, Paula Ellenberg, Sarah Collins, James Cooney, John Zaunders, Lewis Williams, Kirthi Nandha Nair, Ashley Huey Yiing Yap, Nicholas Hirons, Liana Mackiewicz, Merle Dayton, Le Wang, Daniel Sijmons, Mohammad Radwanur Talukder, Allegra Holloway Vickas, Amy W. Chung, Marcel Doerflinger, Marc Pellegrini, Lloyd Einsiedel, Geoffrey Faulkner, Damian F.J. Purcell (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13427564.txt.
Description
Ashley Hirons leads a 2026 study of a virus called HTLV-1c that stays in the body for life and harms the lungs. The team recruited 41 First Nations participants in Alice Springs, in Central Australia, where this subtype is common. Blood tests measured virus levels and sorted immune cells by surface markers. For six donors, the team read whole virus copies inserted into human DNA, one copy at a time.
All infected participants had extra lung-seeking immune cells, and those cells carried much of the virus. Many virus copies were broken yet kept a gene called hbz, which helps the virus persist. Virus material also turned up in sputum from people with lung disease. The findings name two possible drug targets for a neglected infection.
Catalog record
| CREATOR | Ashley Hirons, Natasha Jansz, Georges Khoury, Paula Ellenberg, Sarah Collins, James Cooney, John Zaunders, Lewis Williams, Kirthi Nandha Nair, Ashley Huey Yiing Yap, Nicholas Hirons, Liana Mackiewicz, Merle Dayton, Le Wang, Daniel Sijmons, Mohammad Radwanur Talukder, Allegra Holloway Vickas, Amy W. Chung, Marcel Doerflinger, Marc Pellegrini, Lloyd Einsiedel, Geoffrey Faulkner, Damian F.J. Purcell |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 104408 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |