Antibodies Cross-Reactive with Bundibugyo Virus in Ferrets Vaccinated with Ebola Virus Vaccine
Jordan Wight, Helene Schulz, Logan Banadyga · 2026
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Description
Jordan Wight, Helene Schulz, and Logan Banadyga report cross-reactive antibodies to Bundibugyo virus in ferrets given an Ebola vaccine in a 2026 study. The work matters because the Democratic Republic of the Congo declared a Bundibugyo virus outbreak on 15 May 2026 in Ituri Province, initially reporting 246 suspected cases and 65 deaths. By 13 June, confirmed cases had grown to 695 with 138 deaths, including cases in neighboring Uganda, and the World Health Organization classed the event as an international emergency.
Vaccinated ferrets mounted a prominent but limited antibody response that cross-reacted with Bundibugyo virus despite the vaccine targeting a different ebolavirus. Those immunogenicity data may guide vaccine deployment during the ongoing outbreak.
Catalog record
| CREATOR | Jordan Wight, Helene Schulz, Logan Banadyga |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 7843 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |