Alteration of subgingival microbiome in patients with type 2 diabetes induced by diabetes treatment
Moe Inoue, Akito Sakanaka, Naoto Katakami, Hitoshi Nishizawa, Kazuo Omori, Naohiro Taya, Asuka Ishikawa, Shota Mayumi, Hiroki Takeuchi, Atsuo Amano, Toru Takeshita, Eiichiro Fukusaki, Iichiro Shimomura, Masae Kuboniwa · 2026
Read Alteration of subgingival microbiome in patients with type 2 diabetes induced by diabetes treatment by Moe Inoue, Akito Sakanaka, Naoto Katakami, Hitoshi Nishizawa, Kazuo Omori, Naohiro Taya, Asuka Ishikawa, Shota Mayumi, Hiroki Takeuchi, Atsuo Amano, Toru Takeshita, Eiichiro Fukusaki, Iichiro Shimomura, Masae Kuboniwa (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13426392.txt.
Description
Inoue and colleagues reported in 2026 on how two weeks of intensive blood sugar control changed the bacteria living under the gumline in people with type 2 diabetes. Diabetes and gum disease affect each other in both directions, but the direct effect of treatment on mouth bacteria was unclear. The team studied 29 patients and 29 controls, taking plaque samples and reading full-length gene sequences to name the bacterial species present.
Inoue found that before treatment, patients carried more of four bacteria known for strong links to gum disease than controls did. After treatment, the species that shifted differed between patients whose gum inflammation improved and those whose did not. Changes in plaque bacteria thus tracked changes in gum inflammation, measured by the inflamed surface area score. The work links tighter sugar control with measurable shifts in the mouth community.
Catalog record
| CREATOR | Moe Inoue, Akito Sakanaka, Naoto Katakami, Hitoshi Nishizawa, Kazuo Omori, Naohiro Taya, Asuka Ishikawa, Shota Mayumi, Hiroki Takeuchi, Atsuo Amano, Toru Takeshita, Eiichiro Fukusaki, Iichiro Shimomura, Masae Kuboniwa |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 38 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |