Signal Intensity versus Spatial Resolution: Divergent MPI Performance of SPIONs in Mesenchymal Stromal Cell Labelling

Serbay Ozkan, Elena Ureña Horno, Reilteann Niamh Saul, Mahon L Maguire, Harish Poptani, Marco Giardiello, Patricia Murray · 2026

Read Signal Intensity versus Spatial Resolution: Divergent MPI Performance of SPIONs in Mesenchymal Stromal Cell Labelling by Serbay Ozkan, Elena Ureña Horno, Reilteann Niamh Saul, Mahon L Maguire, Harish Poptani, Marco Giardiello, Patricia Murray (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13426357.txt.

Description

Serbay Ozkan and coauthors compared four iron oxide nanoparticle products for magnetic particle imaging of labeled stem cells in a 2026 study. ProMag, VivoTrax, SynoMag-D, and Ferumoxytol were tested in mouse mesenchymal stromal cells across iron doses and incubation times, using Prussian blue staining for uptake and an ATP assay for cell health. Imaging favors signal strength, while therapy planning also needs fine spatial detail, and the two qualities diverged among products.

Biocompatible candidates advanced to full imaging characterization of labeled cells. Cell tracking teams learn that the brightest particle is not automatically the sharpest, so product choice depends on the imaging job.

Catalog record

CREATORSerbay Ozkan, Elena Ureña Horno, Reilteann Niamh Saul, Mahon L Maguire, Harish Poptani, Marco Giardiello, Patricia Murray
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE42 KB
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13426357

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