Comparative Analysis of SLCO1B1 Gene Polymorphisms in Dyslipidemic and Normolipidemic Patients with Type 2 Diabetes Mellitus Residing at High Altitude
Yong-Hong Ma, Zong-Hong Ji, Chun-Na Han, Sheng-Hua Ma, Jin-Lan Ma, Rui-Xia Zhang, Zhuo-Ma Ni-Yang, Zhi-Xi Zhao, Qi-Fu Zhang · 2026
Read Comparative Analysis of SLCO1B1 Gene Polymorphisms in Dyslipidemic and Normolipidemic Patients with Type 2 Diabetes Mellitus Residing at High Altitude by Yong-Hong Ma, Zong-Hong Ji, Chun-Na Han, Sheng-Hua Ma, Jin-Lan Ma, Rui-Xia Zhang, Zhuo-Ma Ni-Yang, Zhi-Xi Zhao, Qi-Fu Zhang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13426349.txt.
Description
Yong-Hong Ma and coauthors compared a statin-related gene in Tibetan patients with type 2 diabetes at high altitude in a 2026 cross-sectional study. Their sample held 156 patients at Yushu People's Hospital between September 2022 and December 2023, split evenly between normal and abnormal blood lipids. Genotyping targeted two SLCO1B1 variants, 521T>C and 388A>G, using PCR-based methods.
The 521TC genotype appeared in 30.8 percent of the abnormal-lipid group versus 14.1 percent of the normal group, alongside higher triglycerides, total cholesterol, and LDL cholesterol. Both variants tracked with lipid differences, suggesting genetic screening could inform lipid management in this population.
Catalog record
| CREATOR | Yong-Hong Ma, Zong-Hong Ji, Chun-Na Han, Sheng-Hua Ma, Jin-Lan Ma, Rui-Xia Zhang, Zhuo-Ma Ni-Yang, Zhi-Xi Zhao, Qi-Fu Zhang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 30 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |