Olfactory dysfunction and all-cause mortality: a systematic review and meta-analysis

Zhuoshen Lin, Wenjing Liao, Meiqian Xu, Tianlong Li, Lijuan Song, Gui Chen, Huakang Du, Guofei Feng, Zhiming Feng, Qi Zhang, Yabang Chen, Jiayi Liu, Baoxin Peng, Jianlei Xie, Xiaowen Zhang · 2026

Read Olfactory dysfunction and all-cause mortality: a systematic review and meta-analysis by Zhuoshen Lin, Wenjing Liao, Meiqian Xu, Tianlong Li, Lijuan Song, Gui Chen, Huakang Du, Guofei Feng, Zhiming Feng, Qi Zhang, Yabang Chen, Jiayi Liu, Baoxin Peng, Jianlei Xie, Xiaowen Zhang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13425369.txt.

Description

Lin and colleagues published a 2026 review on smell loss as a sign of raised death risk. Poor smell is common in older adults and ties to brain aging. The team pooled cohort studies that tracked smell and later deaths. Fourteen studies qualified, with twelve feeding the main pooled analysis.

Adults with smell loss faced about a fifth higher death risk overall. Correcting for possible publication bias softened the estimate to about nine percent higher. The link survived checks that removed one study at a time. How each study tested smell changed the strength of the link. The authors back standard smell tests in routine checks for older adults. Standard tests would also let clinics build personal risk profiles sooner.

Catalog record

CREATORZhuoshen Lin, Wenjing Liao, Meiqian Xu, Tianlong Li, Lijuan Song, Gui Chen, Huakang Du, Guofei Feng, Zhiming Feng, Qi Zhang, Yabang Chen, Jiayi Liu, Baoxin Peng, Jianlei Xie, Xiaowen Zhang
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE42 KB
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13425369

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