Successful Combination Immunotherapy for Postoperative Recurrence of Esophageal Cancer Following Prior Immune Checkpoint Inhibitor Treatment: A Case Report
Ryo Sakada, Tetsuro Kawazoe, Keita Natsugoe, Yuki Shin, Yoshitaka Imoto, Tomoya Harima, Sho Nambara, Yasuo Tsuda, Tomonori Nakanoko, Koji Ando, Eiji Oki, Tomoharu Yoshizumi · 2026
Read Successful Combination Immunotherapy for Postoperative Recurrence of Esophageal Cancer Following Prior Immune Checkpoint Inhibitor Treatment: A Case Report by Ryo Sakada, Tetsuro Kawazoe, Keita Natsugoe, Yuki Shin, Yoshitaka Imoto, Tomoya Harima, Sho Nambara, Yasuo Tsuda, Tomonori Nakanoko, Koji Ando, Eiji Oki, Tomoharu Yoshizumi (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13425266.txt.
Description
Sakada and colleagues reported in 2026 a case of oesophageal cancer returning after surgery, then controlled long term by layered treatment. The patient was a 68-year-old woman with stage IVB squamous cancer of the gullet that had spread to lymph nodes near the aorta. Three cycles of an immune drug plus chemotherapy shrank the tumor markedly, and robot-assisted surgery then removed the gullet with a clear margin.
Sakada describes how she started a further immune drug after surgery, yet local relapse came five months later. Radiation with chemotherapy followed, and then dual immune blockade with two checkpoint drugs at once. The returning lesions shrank remarkably, and she stayed disease-controlled for 22 months after surgery with no further treatment. The authors argue dual blockade after earlier immune exposure is a real option for selected returning cases, inside tailored team care.
Catalog record
| CREATOR | Ryo Sakada, Tetsuro Kawazoe, Keita Natsugoe, Yuki Shin, Yoshitaka Imoto, Tomoya Harima, Sho Nambara, Yasuo Tsuda, Tomonori Nakanoko, Koji Ando, Eiji Oki, Tomoharu Yoshizumi |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 21 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |