Efficacy of probiotics in preventing atopic dermatitis in infants: A systematic review and meta-analysis
Tianli Wei, Yingxue Ding · 2026
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Description
Wei and Ding pool the trial evidence in this 2026 systematic review and meta-analysis. They ask whether giving probiotics to infants prevents atopic dermatitis. That is the itchy eczema that often opens the allergic march of childhood. Eighteen randomized controlled trials enrolling 10,195 infants aged up to 36 months compared probiotic supplements against placebo or nothing.
The pooled result was a shrug: a risk ratio of 0.94 for developing dermatitis, with a confidence interval spanning 0.72 to 1.25 and a p-value of 0.66, meaning no significant protection in the analysis, and the trials disagreed with each other substantially. Sensitivity checks confirmed the null result, and no publication bias showed. The authors draw a careful distinction: earlier positive meta-analyses leaned on regimens starting in pregnancy, treating mother and baby together, whereas starting probiotics only after birth has failed to show consistent benefit.
Catalog record
| CREATOR | Tianli Wei, Yingxue Ding |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 33 KB |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |